Work of the last 15-20 years demonstrated that gene regulation at the level of RNAs is as important as transcriptional control. In eukaryotic cells, RNA is never naked but associated with various RNA-binding proteins in a well-defined manner forming higher-order complexes. These complexes regulate the temporal and spatial availability of transcripts for translation. They are highly dynamic and change their composition during the life of an mRNA from transcription to degradation. This conference aims to bring together various experts from a broad field of RNA biology with the goal of representing the current state of the mRNA-localization field.